Fernando López-Caamal

Contact Information

E-mail: fernando.lopez.caamal[at]gmail.com

Professional Objective

Research in Control Engineering Theory with applications to Theoretical Biology, (Bio)processes Control, and Mechatronics.

Research Interest

Temporal and spatio-temporal mathematical modelling and analysis of deterministic and stochastic systems. Within the framework of Theoretical Biology, some pathways studied in the past are apoptosis, signal transduction via membrane receptor dynamics (insuline-like grow factor and erythropoietin receptors), and calcium dynamics in neurons.
Control Theory and its application to bioprocesses and mechatronic systems like those involved in applications powered by Solar Energy.


Ph.D., Applied Mathematics (Control Theory, Theoretical Biology)
  • Hamilton Institute, NUIM, Ireland, September 2009 - September 2012
  • Visiting researcher at the Newcastle University, New South Wales, Australia; March 2012 - November 2012
M.Eng., Control Engineering
  • Facultad de Ingeniería, UNAM, México, August 2007 to July 2009
B.S., Mechatronic Engineering
  • Facultad de Ingeniería, UNAM, México, September 2002 to December 2006

List of publications

In preparation (peer reviewed journals)

In peer-reviewed journals

  1. Fernando López-Caamal, et al; Exact probability distributions of selected species in stochastic chemical reaction networks; Bulletin of Mathematical Biology; 2014; doi:10.1007/s11538-014-9985-z; [Open Access]
  2. Fernando López-Caamal, et al; Order Reduction of the Chemical Master Equation via Balanced Realisation; PLoS ONE 9(8): e10352z, 2014; doi:10.1371/journal.pone.0103521; [Open Access]
  3. Diego A. Oyarzún, Jo L. Bramhall, Fernando López-Caamal, Frances M. Richards, Duncan Jodrell, Ben-Fillippo Krippendorff; The EGFR demonstrates linear signal transmission; Integrative Biology; doi:10.1039/C4IB00062E; 2014; [Preprint]
  4. Fernando López-Caamal, Diego A. Oyarzún, Richard H. Middleton, Míriam R. García; Spatial quantification of cytosolic Ca2+ accumulation in nonexcitable cells: An analytical study ; IEEE/ACM Transactions on Computational Biology and Bioinformatics; doi:10.1109/TCBB.2014.2316010; 2014; [Open Access]
  5. Diego A. Oyarzún, Fernando López-Caamal, Míriam R. García, Richard H. Middleton, Andrea Y. Weisse; Cumulative Signal Transmission in Nonlinear Reaction-Diffusion Networks; PLoS ONE; 8(5); doi:10.1371/journal.pone.0062834; 2013; [Open Access]
  6. Fernando López-Caamal, Richard H. Middleton, Heinrich J. Huber; Equilibria and Stability of a Class of Positive Feedback Loops: Mathematical Analysis and its Application to Apoptosis ; Journal of Mathematical Biology; doi:10.1007/s00285-013-0644-z; 2013; [Preprint]
  7. Fernando López-Caamal, Míriam R. García, Richard H. Middelton, Heinrich J. Huber; Positive feedback in the Akt/mTOR pathway and its implications for growth signal progression in skeletal muscle cells: An analytical study; Journal of Theoretical Biology; doi:10.1016/j.jtbi.2012.01.026; 2012; [Preprint]

In peer-reviewed proceedings

  1. López-Caamal F., García M. R., Oyarzún D. A.,Middleton R. H.; Analytic computation of the integrated response in nonlinear reaction-diffusion systems; Conference on Decision and Control; 2012; [Preprint]
  2. López-Caamal F., García M. R., Middleton R. H.; Reducing computational time via order reduction of a class of reaction-diffusion systems; American Control Conference; Montreal; 2012; [Preprint]
  3. López-Caamal F., Oyarzún D. A., Moreno J. A., Kalamatianos D.; Control structure and limitations of biochemical networks; American Control Conference; Baltimore Maryland; 2010; [Preprint]


  1. López-Caamal F.; Contributions to the Analysis of Biochemical Reaction-Di ffusion Networks: Stability, Analysis, and Numerical Solutions; Supervisor: Richard H. Middleton, Co-supervisors: Heinrich J. Huber and Míriam R. García; Jury: Ken Duffy, Jorge Goncalves, John Lowry; PhD Thesis; NUIM
  2. López-Caamal F.; Systems Analysis and Dynamics of Cellular Self-Destruction Systems: Apoptosis; Supervisor: Jaime A. Moreno, Co-supervisor: Dimitrios Kalamatianos; Master Thesis; UNAM : 34990